TTU 02.813
"Personalized medicine: MTB diagnostic, drug monitoring and biomarker analysis"
Short Summary
In the project: Personalized Medicine: Mycobacterium tuberculosis Drug Monitoring and Biomarker Analysis, we develop prevention and treatment strategies that take into account individual variability among people and allow predictions to accurately identify who will benefit most from specific therapies, while saving costs and side effects. In Heidelberg, we carry out the cost-effectiveness modelling studies to support the implementation considerations.
Highlights
- Modelling informed WHO meeting on target product profiles for treatment monitoring
- Zimmer AJ, Lainati F, Aguilera Vasquez N, Chedid C, McGrath S, Benedetti A, MacLean E, Ruhwald M, Denkinger CM, Kohli M. Biomarkers That Correlate with Active Pulmonary Tuberculosis Treatment Response: a Systematic Review and Meta-analysis. J Clin Microbiol. 2022 Feb 16;60(2):e0185921
